SMS reminders to improve the uptake and timeliness of the primary immunisation series in infants: a multi-centre randomised controlled trial
DOI:
https://doi.org/10.33321/cdi.2022.46.15Keywords:
immunisation, timeliness, children, short messaging service, randomised controlled trialAbstract
Background
Immunisation timeliness continues to present challenges to achieving optimal vaccine coverage in infancy, particularly in disadvantaged groups and Australian First Nations infants. We aimed to determine whether a tailored, educational SMS reminder improves the timeliness of immunisation in infants up to seven months of age.
Methods
A pragmatic, three-arm, parallel-group, randomised controlled trial of immunisation reminders was conducted in two First-Nations-specific primary health care centres and two public hospital antenatal clinics in South East Queensland, Australia. Live-born infants of mothers enrolled during pregnancy were randomised at birth and followed to eight months of age. One group received a simple SMS reminder at two weeks before, the week of, and two weeks after the due date for immunisation at two, four and six months of age. The second group received a tailored SMS with an educational message at two weeks before and on the date immunisations were due; those not immunised two weeks following the due date were offered support to immunise the baby. Controls received no intervention or contact until the baby turned seven months of age. The primary outcome was the proportion of infants age-appropriately vaccinated at seven months of age as recorded on the Australian Immunisation Register. Secondary outcomes included vaccination status at three and five months of age.
Results
Between 30 May 2016 and 24 May 2018, one hundred and ninety-six infants (31% First Nations infants) were randomised. At seven months of age, 54/65 (83.1%) infants in the educational SMS ± additional support group (ESMS±S) were age-appropriately immunised, compared to 45/64 (70.3%) in the simple SMS group and 45/67 (67.2%) in controls. Differences were most marked at five months of age: ESMS±S 95.5%; simple SMS 73.4%; controls 75.8%. The difference between the ESMS±S group and the other two groups at seven months of age was no longer apparent when those who received additional support beyond the SMS were assumed to have not been vaccinated if that support had not been received.
Discussion
A tailored SMS reminder system using an educational message and with provision of additional support to mothers is more effective in improving immunisation timeliness in infants at three and five months of age than a simple message and no intervention. The additional support was required at seven months of age in order to achieve higher coverage in the ESMS±S group.
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References
Hull B, Hendry A, Dey A, Macartney K, Beard F. Immunisation Coverage Annual Report 2019. Commun Dis Intell (2018). 2021;45. doi: https://doi.org/10.33321/cdi.2021.45.18.
Moore HC, Fathima P, Gidding HF, de Klerk N, Liu B, Sheppeard V et al. Assessment of on-time vaccination coverage in population subgroups: a record linkage cohort study. Vaccine. 2018;36(28):4062–9. doi: https://doi.org/10.1016/j.vaccine.2018.05.084.
O’Grady KA, Krause V, Andrews R. Immunisation coverage in Australian Indigenous children: time to move the goal posts. Vaccine. 2009;27(2):307–12. doi: https://doi.org/10.1016/j.vaccine.2008.09.096.
Naidu L, Chiu C, Habig A, Lowbridge C, Jayasinghe S, Wang H et al. Vaccine preventable diseases and vaccination coverage in Aboriginal and Torres Strait Islander people, Australia 2006–2010. Commun Dis Intell Q Rep. 2013;37(Suppl):S1–95.
Royle J, Lambert SB. Fifty years of immunisation in Australia (1964-2014): the increasing opportunity to prevent diseases. J Paediatr Child Health. 2015;51(1):16–20. doi: https://doi.org/10.1111/jpc.12796.
Lovie-Toon YG, Hall KK, Chang AB, Anderson J, O’Grady KA. Immunisation timeliness in a cohort of urban Aboriginal and Torres Strait Islander children. BMC Public Health. 2016;16(1):1159. doi: https://doi.org/10.1186/s12889-016-3825-z.
Rodgers A, Corbett T, Bramley D, Riddell T, Wills M, Lin R-B et al. Do u smoke after txt? Results of a randomised trial of smoking cessation using mobile phone text messaging. Tob Control. 2005;14(4):255–61. doi: https://doi.org/10.1136/tc.2005.011577.
Bramley D, Riddell T, Whittaker R, Corbett T, Lin R-B, Wills M et al. Smoking cessation using mobile phone text messaging is as effective in Maori as non-Maori. N Z Med J. 2005;118(1216):U1494.
Kunutsor S, Walley J, Katabira E, Muchuro S, Balidawa H, Namagala E et al. Using mobile phones to improve clinic attendance amongst an antiretroviral treatment cohort in rural Uganda: a cross-sectional and prospective study. AIDS Behav. 2010;14(6):1347–52. doi: https://doi.org/10.1007/s10461-010-9780-2.
National Health and Medical Research Council. National Statement on Ethical Conduct in Human Research (2007). Canberra: Australian Government; 2007.
Jacobson Vann JC, Jacobson RM, Coyne-Beasley T, Asafu-Adjei JK, Szilagyi PG. Patient reminder and recall interventions to improve immunization rates. Cochrane Database Syst Rev. 2018;1:CD003941. doi: https://doi.org/10.1002/14651858.CD003941.pub3.
Mekonnen ZA, Gelaye KA, Were MC, Gashu KD, Tilahun BC. Effect of mobile text message reminders on routine childhood vaccination: a systematic review and meta-analysis. Syst Rev. 2019;8(1):154. doi: https://doi.org/10.1186/s13643-019-1054-0.
Eze P, Lawani LO, Acharya Y. Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis. BMJ Glob Health. 2021;6(7). doi: https://doi.org/10.1136/bmjgh-2021-005035.
Menzies R, Heron L, Lampard J, McMillan M, Joseph T, Chan J et al. A randomised controlled trial of SMS messaging and calendar reminders to improve vaccination timeliness in infants. Vaccine. 2020;38(15):3137–42. doi: https://doi.org/10.1016/j.vaccine.2020.02.045.
Gibson DG, Ochieng B, Kagucia EW, Were J, Hayford K, Moulton LH et al. Mobile phone-delivered reminders and incentives to improve childhood immunisation coverage and timeliness in Kenya (M-SIMU): a cluster randomised controlled trial. Lancet Glob Health. 2017;5(4):e428–38. doi: https://doi.org/10.1016/S2214-109X(17)30072-4.
Kazi AM. The role of mobile phone-based interventions to improve routine childhood immunisation coverage. Lancet Glob Health. 2017;5(4):e377–8. doi: https://doi.org/10.1016/S2214-109X(17)30088-8.
Becker MH. The Health Belief Model and personal behaviour. Health Educ Monogr. 1974;2:324–508.
Gidding HF, Flack LK, Sheridan S, Liu B, Fathima P, Sheppeard V et al. Infant, maternal and demographic predictors of delayed vaccination: a population-based cohort study. Vaccine. 2020;38(38)6057–64. doi: https://doi.org/10.1016/j.vaccine.2019.09.091.
McCurdy K, Daro D, Anisfeld E, Katzev A, Keim A, Lecroy C et al. Understanding maternal intentions to engage in home visiting programs. Child Youth Serv Rev. 2006;28(10):1195–212. doi: https://doi.org/10.1016/j.childyouth.2005.11.010.
Tandon SD, Parillo K, Mercer C, Keefer M, Duggan AK. Engagement in paraprofessional home visitation: families’ reasons for enrollment and program response to identified reasons. Womens Health Issues. 2008;18(2):118–29. doi: https://doi.org/10.1016/j.whi.2007.10.005.
Munns A, Watts R, Hegney D, Walker R. Effectiveness and experiences of families and support workers participating in peer-led parenting support programs delivered as home visiting programs: a comprehensive systematic review. JBI Database System Rev Implement Rep. 2016;14(10):167–208. doi: https://doi.org/10.11124/JBISRIR-2016-003166.
Kaufman J, Attwell K, Tuckerman J, O’Sullivan J, Omer SB, Leask J et al. Feasibility and acceptability of the multi-component P3-MumBubVax antenatal intervention to promote maternal and childhood vaccination: a pilot study. Vaccine. 2020;38(24):4024–31. doi: https://doi.org/10.1016/j.vaccine.2020.04.010.
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