SARS-CoV-2 RT-PCR test results across symptomatic COVID-19 cases in Auckland, New Zealand, February–June 2020
DOI:
https://doi.org/10.33321/cdi.2021.45.32Keywords:
coronavirus disease 2019, COVID-19, severe acute respiratory syndrome-related coronavirus-2, SARS-CoV-2Abstract
During the first wave of COVID-19 transmission in New Zealand, a review of RT-PCR testing in all symptomatic cases reported in the Auckland Region found 74% of test results to have been positive. Detection rate was superior for nasopharyngeal swabs than for oropharyngeal samples, and highest one week after symptom onset. Certain symptom presentations may associate with these cases returning negative results, with dyspnoea reported by a greater proportion of cases who tested negative.
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References
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–33.
Australian Government Department of Health. Eliminating COVID-19 a false hope. [Internet.] Canberra: Australian Government Department of Health; 2020. Available from: https://www.health.gov.au/news/eliminating-covid-19-a-false-hope.
Environmental Science and Research Institute (ESR), Ministry of Health New Zealand. New Zealand Covid-19 Surveillance Dashboard. [Internet.] Wellington: ESR; 2020. Available from: https://nzcoviddashboard.esr.cri.nz/#!/.
Giles ML, Wallace EM, Alpren C, Brady N, Crouch S, Romanes F et al. Suppression of SARS-CoV-2 after a second wave in Victoria, Australia. Clin Infect Dis. 2020. doi: https://doi.org/10.1093/cid/ciaa1882.
Cheng MP, Papenburg J, Desjardins M, Kanjilal S, Quach C, Libman M et al. Diagnostic testing for severe acute respiratory syndrome–related coronavirus-2. Ann Intern Med. 2020;172(11):726–34.
Marcotte LM, Liao JM. Incorporating test characteristics into SARS-CoV-2 testing policy—sense and sensitivity. JAMA Health Forum. 2020. doi:10.1001/jamahealthforum.2020.0448.
Arons MM, Hatfield KM, Reddy SC, Kimball A, James A, Jacobs JR et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med. 2020;382(22):2081–90.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054–62.
Wang W, Xu Y, Gao R, Lu R, Han K, Wu G et al. Detection of SARS-CoV-2 in different types of clinical specimens. JAMA. 2020;323(18):1843–4.
Kucirka LM, Lauer SA, Laeyendecker O, Boon D, Lessler J. Variation in false-negative rate of reverse transcriptase polymerase chain reaction–Based SARS-CoV-2 tests by time since exposure. Ann Intern Med. 2020;173(4):262–7.
Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N Engl J Med. 2020;382(12):1177–9.
He X, Lau EHY, Wu P, Deng X, Wang J, Hao X et al. Temporal dynamics in viral shedding and transmissibility of COVID-19. Nat Med. 2020;26(5):672–5.
Wölfel R, Corman VM, Guggemos W, Seilmaier M, Zange S, Müller MA et al. Virological assessment of hospitalized patients with COVID-2019. Nature. 2020;581(7809):465–9.
ESR. New Zealand influenza intelligence report: week ending 29 September 2019. Wellington: ESR; 2019. Available from: https://www.esr.cri.nz/assets/Influenza-Surveillance-Intelligence-Report-2019_WE29Sept19.pdf.
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