Australia’s national zoster vaccination program: Knowledge, attitudes and behaviour of general practitioners

Authors

  • Harunor Rashid National Centre for Immunisation Research and Surveillance (NCIRS), Kids Research, The Children’s Hospital at Westmead, Sydney, New South Wales, Australia;Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia
  • Aditi Dey National Centre for Immunisation Research and Surveillance (NCIRS), Kids Research, The Children’s Hospital at Westmead, Sydney, New South Wales, Australia;Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia
  • Ramesh Manocha Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia;Healthed, PO Box 500, Burwood, New South Wales, Australia.
  • Mohamed Tashani National Centre for Immunisation Research and Surveillance (NCIRS), Kids Research, The Children’s Hospital at Westmead, Sydney, New South Wales, Australia;Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia
  • Kristine Macartney National Centre for Immunisation Research and Surveillance (NCIRS), Kids Research, The Children’s Hospital at Westmead, Sydney, New South Wales, Australia;Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia
  • Frank Beard National Centre for Immunisation Research and Surveillance (NCIRS), Kids Research, The Children’s Hospital at Westmead, Sydney, New South Wales, Australia;Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia

DOI:

https://doi.org/10.33321/cdi.2020.44.59

Keywords:

general practitioner, herpes zoster, immunocompromise, national zoster vaccination program, post-herpetic neuralgia, zoster vaccine

Abstract

Objectives

To assess knowledge, attitudes and behaviour of Australian general practitioners (GPs) regarding herpes zoster vaccination under the National Immunisation Program (NIP) from 2016 for adults aged 70–79 years.

Design, setting, participants

National cross-sectional online survey of GPs, October–November 2017.

Outcome measures

Knowledge, attitudes and behaviour regarding zoster vaccination, including challenges experienced and recommendations for improvement.

Results

Of the 1026 GPs who responded (response rate 7.9%), 98.5% were aware that zoster vaccine is NIP-funded for adults aged 70–79 years and 85.4% that it is recommended for age 60–69 years; however, 51.3% incorrectly thought it is routinely recommended for age 50–59 years. A minority (4.6%) incorrectly believed that being immunocompromised is not a contraindication to zoster vaccination and 16.0% that it cannot be co-administered with influenza or pneumococcal vaccine. Almost half (48.9%) rarely or never reported zoster vaccination data to the Australian Immunisation Register (AIR). Challenges perceived included lack of adequate information on vaccine contraindications; efficacy and safety concerns; and difficulty applying age criteria for NIP eligibility in general practice. Respondents indicated a desire for program expansion to include younger and older adult age groups.

Conclusion

This Australian GP survey, conducted one year after the introduction of the national zoster vaccination program, identified some knowledge gaps. A repeat survey of GPs is warranted to determine whether these issues persist, particularly regarding contraindication to vaccination for immunocompromised individuals. We encourage all GPs to offer zoster vaccination in line with current Australian evidence-based guidelines, particularly for the NIP-funded 70–79 years cohort; ensuring compliance with relevant contraindications; and reporting to AIR.

Downloads

Download data is not yet available.

References

Cohen JI. Clinical practice: herpes zoster. N Engl J Med. 2013;369(3):255–63.

Stein AN, Britt H, Harrison C, Conway EL, Cunningham A, Macintyre CR. Herpes zoster burden of illness and health care resource utilisation in the Australian population aged 50 years and older. Vaccine. 2009;27(4):520–9.

National Centre for Immunisation Research and Surveillance (NCIRS). Significant events in zoster vaccination practice in Australia. Sydney: NCIRS; 2018. [Accessed on 7 May 2020.] Available from: http://www.ncirs.org.au/sites/default/files/2018-12/Zoster-history-Dec-2018.pdf.

Jayasinghe S, Sheridan S, Macartney K. Herpes zoster vaccination in Australia: what’s available and who benefits? Aust Prescr. 2020;43(1):2–6.

Australian Technical Advisory Group on Immunisation (ATAGI). The Australian Immunisation Handbook, 10th ed: Zoster (herpes zoster). [Internet.] Canberra: Australian Government Department of Health; 2018. [Accessed on 7 May 2020.] Available from: https://immunisationhandbook.health.gov.au/vaccine-preventable-diseases/zoster-herpes-zoster.

Oxman MN, Levin MJ, Johnson GR, Schmader KE, Straus SE, Gelb LD et al. A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults. N Engl J Med. 2005;352(22):2271–84.

Morrison VA, Johnson GR, Schmader KE, Levin MJ, Zhang JH, Looney DJ et al. Long-term persistence of zoster vaccine efficacy. Clin Infect Dis. 2015;60(6):900–9.

Dooling K, Guo A, Leung J, Belongia E, Harpaz R. Performance of zoster vaccine live (Zostavax): a systematic review of 12 years of experimental and observational evidence. Open Forum Infect Dis. 2017;4(Suppl 1):S412–3.

Willis ED, Woodward M, Brown E, Popmihajlov Z, Saddier P, Annunziato PW et al. Herpes zoster vaccine live: a 10 year review of post-marketing safety experience. Vaccine. 2017;35(52):7231–9.

Strezova A, Godeaux O, Aggarwal N, Leroux-Roels G, Lopez-Fauqued M, Van Damme P et al. A randomized lot-to-lot immunogenicity consistency study of the candidate zoster vaccine HZ/su. Vaccine 2017;35(48 Pt B):6700–6.

NCIRS. Evaluation of the national shingles vaccination program process and early impact evaluation. Sydney: NCIRS; 2019. [Accessed on 7 May 2020.] Available from: http://ncirs.org.au/sites/default/files/2019-03/ZOS_201903_EvaluationNationalShinglesVaccinationReportFINAL.pdf.

NCIRS. Program evaluation. [Internet.] Sydney: NCIRS. [Accessed on 14 May 2020.] Available from: http://ncirs.org.au/our-work/program-evaluation.

Klein NP, Bartlett J, Fireman B, Marks MA, Hansen J, Lewis E et al. Long-term effectiveness of zoster vaccine live for postherpetic neuralgia prevention. Vaccine. 2019;37(36):5422–7.

Alexander KE, Tong PL, Macartney K, Beresford R, Sheppeard V, Gupta M. Live zoster vaccination in an immunocompromised patient leading to death secondary to disseminated varicella zoster virus infection. Vaccine. 2018;36(27):3890–93.

Dey A, Wang H, Quinn H, Hiam R, Wood N, Beard F, et al. Surveillance of adverse events following immunisation in Australia annual report, 2017. Commun Dis Intell (2018). 2019;43. doi: https://doi.org/10.33321/cdi.2019.43.29.

Therapeutic Goods Administration (TGA). Zostavax vaccine. Safety advisory – not to be used in patients with compromised immune function. [Internet.] Canberra: Australian Government Department of Health, TGA; 2017. [Accessed on 16 February 2020.] Available from: https://www.tga.gov.au/alert/zostavax-vaccine.

NCIRS. Exploratory analysis of the first 2 years of adult vaccination data recorded on AIR. Sydney: NCIRS; 2019. [Accessed on 14 May 2020.] Available from: http://www.ncirs.org.au/sites/default/files/2019-12/Analysis%20of%20adult%20vaccination%20data%20on%20AIR_Nov%202019.pdf.

Lin J, Wood JG, Bernardo C, Stocks NP, Liu B. Herpes zoster vaccine coverage in Australia before and after introduction of a national vaccination program. Vaccine. 2020;38(20):3646–52.

Nolan TM. The Australian model of immunization advice and vaccine funding. Vaccine. 2010;28(Suppl 1):A76–83.

Pharmaceutical Benefits Advisory Committee (PBAC). Public Summary Document – November 2014 PBAC Meeting: 7.9 Zoster Virus Vaccine Live. Canberra: Australian Government Department of Health, Pharmaceutical Benefits Scheme, PBAC; 2014. [Accessed on 16 February 2020.] Available from: http://www.pbs.gov.au/industry/listing/elements/pbac-meetings/psd/2014-11/files/zoster-vaccine-psd-11-2014.pdf.

Australian Government Department of Health. General practice: 2016 Factsheet. Canberra: Australian Government Department of Health; 2017. [Accessed on 14 May 2020.] Available from: https://hwd.health.gov.au/webapi/customer/documents/factsheets/2016/General%20practice.pdf

Royal Australian College of General Practitioners (RACGP). General Practice: Health of the Nation 2017. Melbourne: RACGP; 2017. [Accessed on 14 May 2020.] Available from: https://www.racgp.org.au/FSDEDEV/media/documents/Special%20events/Health-of-the-Nation-2017-report.pdf.

Downloads

Published

15/07/20

How to Cite

Rashid, Harunor, Aditi Dey, Ramesh Manocha, Mohamed Tashani, Kristine Macartney, and Frank Beard. 2020. “Australia’s National Zoster Vaccination Program: Knowledge, Attitudes and Behaviour of General Practitioners ”. Communicable Diseases Intelligence 44 (July). https://doi.org/10.33321/cdi.2020.44.59.

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 > >>