The epidemiology of amoebiasis in the Northern Territory of Australia over 20 years (2005 – 2024)
DOI:
https://doi.org/10.33321/cdi.2025.49.058Keywords:
amoebiasis, epidemiology, Entamoeba histolytica, Northern Territory, AustraliaAbstract
Amoebiasis is an important parasitic cause of morbidity and mortality worldwide and is known to be endemic in Northern Australia. The Northern Territory is the only jurisdiction in Australia where amoebiasis is notifiable. The epidemiology of amoebiasis across Australia is not well described. We undertook this retrospective study to describe the epidemiology of amoebiasis in the Northern Territory from 1 January 2005 to 30 June 2024. Data were obtained from the Northern Territory Notifiable Disease System. Of the 26 cases identified, most were men (81%), non-Indigenous (88%) and with infection overseas acquired (69%). Most had extra-intestinal manifestations (65%), and most required hospitalisation (54%). There was one death related to amoebic splenic abscess. Of the seven locally acquired cases, all resided in the Top End and Katherine regions, and two were children. The highest annual incidence occurred in 2024, all of whom were returned travellers. This study highlights that amoebiasis in the Northern Territory is both endemic and overseas acquired, and that clinicians should consider this differential diagnosis in people presenting with gastrointestinal symptoms and initiate timely testing and appropriate treatment.
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Bercu TE, Petri WA, Behm BW. Amebic colitis: new insights into pathogenesis and treatment. Curr Gastroenterol Rep. 2007;9(5):429–33. doi: https://doi.org/10.1007/s11894-007-0054-8.
Nasrallah J, Akhoundi M, Haouchine D, Marteau A, Mantelet S, Wind P et al. Updates on the worldwide burden of amoebiasis: a case series and literature review. J Infect Public Health. 2022;15(10):1134–41. doi: https://doi.org/10.1016/j.jiph.2022.08.013.
Outtara M, N’Guéssan NA, Yapi A, N’Goran EK. Correction: prevalence and spatial distribution of Entamoeba histolytica/dispar and Giardia lamblia among school children in Agboville Area (Côte d'Ivoire). PLOS Negl Trop Dis. 2010;4(2). doi: https://doi.org/10.1371/annotation/a28fd8eb-b0a9-47f1-935c-7912050dc19b.
van Hal SJ, Stark DJ, Fotedar R, Marriott D, Ellis JT, Harkness JL. Amoebiasis: current status in Australia. Med J Aust. 2007;186(8):412–6. doi: https://doi.org/10.5694/j.1326-5377.2007.tb00975.x.
McCarthy JS, Peacock D, Trown KP, Bade P, Petri WA, Currie BJ. Endemic invasive amoebiasis in northern Australia. Med J Aust. 2002;177(10):570. doi: https://doi.org/10.5694/j.1326-5377.2002.tb04957.x.
Weinke T, Friedrich-Jaenicke B, Hopp P, Janitschke K. Prevalence and clinical importance of Entamoeba histolytica in two high-risk groups: travelers returning from the tropics and male homosexuals. J Infect Dis. 1990;161(5):1029–31. doi: https://doi.org/10.1093/infdis/161.5.1029.
Stark DJ, Fotedar R, Ellis JT, Harkness JL. Locally acquired infection with Entamoeba histolytica in men who have sex with men in Australia. Med J Aust. 2006;185(8):417. doi: https://doi.org/10.5694/j.1326-5377.2006.tb00636.x.
Arora A, Sandip S, Mukund A, Patidar Y. Fulminant necrotizing amoebic colitis. Travel Med Infect Dis. 2012;10(5–6):270–1. doi: https://doi.org/10.1016/j.tmaid.2012.03.009.
Northern Territory Government Register of Legislation (NT Legislation). Notifiable Diseases Act 1981. [Legislation.] Darwin: NT Legislation; 27 November 2023. [Accessed on 25 November 2024.] Available from: https://legislation.nt.gov.au/Legislation/NOTIFIABLE-DISEASES-ACT-1981.
Northern Territory Government Department of Treasury and Finance. Northern Territory Economy: Population. [Webpage.] Darwin: Northern Territory Government; 2024. [Accessed on 25 November 2024.] Available from: https://nteconomy.nt.gov.au/population.
Australian Bureau of Statistics. Snapshot of Northern Territory: high level summary data for Northern Territory in 2021. [Webpage.] Canberra: Australian Bureau of Statistics; 28 June 2022. [Accessed on 25 November 2024.] Available from: https://www.abs.gov.au/articles/snapshot-nt-2021.
Domazetovska A, Lee R, Adhikari C, Watts M, Gilroy N, Stark D et al. A 12-year retrospective study of invasive amoebiasis in Western Sydney: evidence of local acquisition. Trop Med Infect Dis. 2018;3(3):73. doi: https://doi.org/10.3390/tropicalmed3030073.
United States Centers for Disease Control and Prevention (US CDC). Laboratory diagnosis of amoebiasis. Entamoeba histolytica and Entamoeba dispar. Atlanta: United States Government Department of Health and Human Services, US CDC. [Accessed on 25 November 2024.] Available from: https://www.cdc.gov/dpdx/resources/pdf/benchaids/entamoeba_benchaid.pdf.
NT Heath, Centre for Disease Control (NT CDC). Amoebiasis. Notifiable Diseases Public Health Management Guide (fourth edition). Darwin: NT CDC; August 2024. Available from: http://internal.health.nt.gov.au/teamsites/cdc/Public%20Health%20Response/Notifiable%20diseases%20public%20health%20management%20guide%204th%20edition.pdf
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