SARS-CoV-2 public health investigation in an aged care facility and challenges with serological screening in low pre-test probability settings
DOI:
https://doi.org/10.33321/cdi.2021.45.42Keywords:
SARS-CoV-2, serosurvey, aged care facilityAbstract
Findings from a study in Queensland support the use of the SARS-CoV-2 MIA followed by neutralisation testing confirmation for screening in large-scale seroprevalence studies in low-pretest probability environments such as aged care facilities.
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Gidding HF, Machalek DA, Hendry AJ, Quinn HE, Vette K, Beard FH et al. Seroprevalence of SARS-CoV-2-specific antibodies in Sydney after the first epidemic wave of 2020. Med J Aust. 2021;214(4):179–85. doi: https://doi.org/10.5694/mja2.50940.
Bajema KL, Wiegand RE, Cuffe K, Patel SV, Iachan R, Lim T et al. Estimated SARS-CoV-2 seroprevalence in the US as of September 2020. JAMA Intern Med. 2020;e207976. doi: https://doi.org/10.1001/jamainternmed.2020.7976.
Public Health Laboratory Network (PHLN). Public Health Laboratory Network Guidance for serological testing in COVID-19, version 1.3. Canberra: Australian Government Department of Health; 3 September 2020. Available from: https://www.health.gov.au/sites/default/files/documents/2020/09/phln-guidance-for-serological-testing-in-covid-19-phln-guidance-on-serological-testing-in-covid-19.pdf.
State Health Emergency Coordination Centre (SHECC). Situation Report No. 159. Brisbane: Queensland Government, Queensland Health, SHECC; October 2021.
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