Symptom profile of COVID-19 in children in the Metro South area of Brisbane, during the first SARS-CoV-2 Omicron wave: a population-based survey
DOI:
https://doi.org/10.33321/cdi.2025.49.025Keywords:
COVID-19, children, symptoms, Omicron, gastrointestinal, SARS-CoV-2Abstract
Background
An increase in gastrointestinal infections in Early Childhood Education and Care notified to the public health unit in the Metro South area of Brisbane, Australia, coincided with the peak of the first Omicron wave in 2022. This made public health messaging and advice on outbreak management challenging. We hypothesised that gastrointestinal symptoms were a feature of the Omicron variant infection. At the time, there was a paucity of data on presenting symptoms of coronavirus disease 2019 (COVID-19) by the Omicron variant of SARS-CoV-2 among Australian children.
Objectives
To describe the symptom profile of COVID-19 in children residing in a large Metropolitan area in Queensland during the first Omicron wave.
Methods, setting, and participants
Participation was invited from cases of COVID-19 notified in those 17 years or younger via the Queensland Notifiable Conditions System between 7 February and 13 March 2022. A retrospective self-reported survey of these children was conducted at the end of May 2022 to understand the symptom profile and severity of infection.
Results
Of the 285 responses received, 91% reported being symptomatic; the most common symptoms noted were fever (75%), fatigue (57%), sore throat (55%), headache (55%), cough (50%) and runny nose (48%). Gastrointestinal symptoms were reported in 33% of cases. A majority of the children had either fever (31%) or respiratory symptoms (40%) as the first symptom, with only 7% reporting gastrointestinal symptoms as their first symptom. Close to three-quarters of the children had symptoms that lasted for four days or less. Medical advice/treatment was sought by 17% of symptomatic cases.
Conclusions
The majority of children with COVID-19 during the Omicron wave had fever or respiratory related symptoms as their first symptoms. Gastrointestinal symptoms were uncommon as the first symptom or in conjunction with other symptoms. Understanding the symptom profile in children helps inform institutional settings of their infection control practices and public health messaging.
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References
Puoti MG, Rybak A, Kiparissi F, Gaynor E, Borrelli O. SARS-CoV-2 and the gastrointestinal tract in children. Front Pediatr. 2021;9:617980. doi: https://doi.org/10.3389/fped.2021.617980.
Molteni E, Sudre CH, Canas LS, Bhopal SS, Hughes RC, Antonelli M et al. Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2. Lancet Child Adolesc Health. 2021;5(10):708–18. doi: https://doi.org/10.1016/S2352-4642(21)00198-X.
Williams P, Koirala A, Saravanos GL, Lopez LK, Glover C, Sharma K et al. COVID-19 in New South Wales children during 2021: severity and clinical spectrum. Med J Aust. 2022;217(6):303–10. doi: https://doi.org/10.5694/mja2.51661.
Metro South Public Health Unit. Health Indicators Report: Metro South Health. Brisbane: Queensland Government Department of Health, Metro South Health; 25 November 2022. Available from: https://www.metrosouth.health.qld.gov.au/__data/assets/pdf_file/0025/291454/health-indicators-22-msh.pdf.
Chang H, Zhang X, Su H, Cai J, Liu X, Li J et al. Epidemiological characteristics of paediatric Omicron infection during the outbreak of SARS-CoV-2 infection during March-May in 2022 in Shanghai, China. Epidemiol Infect. 2023;151:e81. doi: https://doi.org/10.1017/S0950268823000663.
Mastrolia MV, De Cillia C, Orlandi M, Abu-Rumeileh S, Maccora I, Maniscalco V et al. Clinical syndromes related to SARS-CoV-2 infection and vaccination in pediatric age: a narrative review. Medicina (Kaunas). 2023;59(11):2027. doi: https://doi.org/10.3390/medicina59112027.
Shirbhate E, Pandey J, Patel VK, Kamal M, Jawaid T, Gorain B et al. Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention. Pharmacol Rep. 2021;73(6):1539–50. doi: https://doi.org/10.1007/s43440-021-00303-6.
Wang X, Chang H, Tian H, Zhu Y, Li J, Wei Z et al. Epidemiological and clinical features of SARS-CoV-2 infection in children during the outbreak of Omicron variant in Shanghai, March 7–31, 2022. Influenza Other Respir Viruses. 2022;16(6):1059–65. doi: https://doi.org/10.1111/irv.13044.
Tagarro A, Coya ON, Pérez-Villena A, Iglesias B, Navas A, Aguilera-Alonso D et al. Features of COVID-19 in children during the Omicron wave compared with previous waves in Madrid, Spain. Pediatr Infect Dis J. 2022;41(5):e249–51. doi: https://doi.org/10.1097/INF.0000000000003482.
Taytard J, Prevost B, Schnuriger A, Aubertin G, Berdah L, Bitton L et al. SARS-CoV-2 B.1.1.529 (Omicron) variant causes an unprecedented surge in children hospitalizations and distinct clinical presentation compared to the SARS-CoV-2 B.1.617.2 (Delta) variant. Front Pediatr. 2022;10:932170. doi: https://doi.org/10.3389/fped.2022.932170.
Bitar RR, Alattas B, Azaz A, Rawat D, Miqdady M. Gastrointestinal manifestations in children with COVID-19 infection: retrospective tertiary center experience. Front Pediatr. 2022;10:925520. doi: https://doi.org/10.3389/fped.2022.925520.
Butt AA, Dargham SR, Loka S, Shaik RM, Chemaitelly H, Tang P et al. Coronavirus disease 2019 disease severity in children infected with the Omicron variant. Clin Infect Dis. 2022;75(1):e361–7. doi: https://doi.org/10.1093/cid/ciac275.
Li YC, Ma Z, Zhong HY, You HL. Clinical characteristics of children with omicron SARS-CoV-2 infection in Changchun, China from March to April 2022: a retrospective study. Front Pediatr. 2022;10:990944. doi: https://doi.org/10.3389/fped.2022.990944.
Singh D, Joshi K, Samuel A, Patra J, Mahindroo N. Alcohol-based hand sanitisers as first line of defence against SARS-CoV-2: a review of biology, chemistry and formulations. Epidemiol Infect. 2020;148:e229. doi: https://doi.org/10.1017/s0950268820002319.
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