Rotavirus infection - the need for a vaccine

Authors

  • Ruth Bishop Department of Gastroenterology and Clinical Nutrition, Royal Children’s Hospital, Parkville, Victoria 3052
  • Graeme Barnes Department of Gastroenterology and Clinical Nutrition, Royal Children’s Hospital, Parkville, Victoria 3052

DOI:

https://doi.org/10.33321/cdi.1996.20.43

Abstract

Primary rotavirus infection in young children can cause severe acute diarrhoea requiring hospitalisation for treatment of dehydration. Morbidity and mortality rates in children throughout the world are sufficient to justify the development of a vaccine. Current strategies are aimed at the development of a live oral attenuated rotavirus vaccine to be given in the first two to three months of life, preferably in association with oral poliomyelitis vaccine.

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References

Brandt C, Glass RI. Impact of diarrheal diseases worldwide. In: Kapikian AZ, ed. Viral infections of the gastrointestinal tract, 2nd ed. New York: Marcel Dekker, 1994:1-26.

Bishop RF. Natural history of human rotavirus infection. In: Kapikian AZ, ed. Viral infections of the gastrointestinal tract, 2nd ed. New York: Marcel Dekker, 1994: 131-167.

Kapikian AZ, Chanock RM. Rotaviruses. In: Fields BN et al. Field’s Virology, 3rd ed. Philadelphia: Lippincott-Raven, 1996:1657-1708.

Bishop RF. Development of candidate rotavirus vaccines. Vaccine II: 1993;247-254.

Bernstein DI, Glass RI, Rodgers G et al. Evaluation of rhesus rotavirus monovalent and tetravalent reassortant vaccines in US children. JAMA 1995; 273:1191-1196.

Rodriguez WJ, Kim HW, Brandt CD et al.Longitudinal study of rotavirus infection and gastroenteritis in families served by a paediatric medical practice: clinical and epidemiologic observations. Pediatr Infect Dis 1987;6:170-176.

Masendycz PJ, Unicomb LE, Kirkwood CD, Bishop RF. Rotavirus serotypes causing severe acute diarrhoea in young children in six Australian cities 1989 to 1992. J Clin Microbiol 1994; 32:2315-2317.

Ferson MJ. Hospitalisations for rotavirus gastroenteritis among children under 5 years of age in New South Wales. Med J Aust 1996; 164:273-277.

Ferson MJ. Direct and indirect costs of a rotavirus outbreak in child care. Comm Dis Intell 1995;19:4-6.

Palombo EA, Bugg HC, Masendycz PJ. Multiple gene rotavirus reassortants responsible for an outbreak of gastroenteritis in central and northern Australia. J Gen Virol 1996 (in press).

Bishop RS, Barnes GL, Cipriani E, Lund JS. Clinical immunity after neonatal rotavirus infection. A prospective longitudinal study in young children. N Engl J Med 1983;309:72-76.

Crawley JMS, Bishop RF, Barnes GL. Rotavirus gastroenteritis in infants aged 0-6 months in Melbourne, Australia: implications for vaccination. J Paediatr Child Health 1993; 29:219-221.

Smith JC, Haddex AC, Teutsch SM, Glass RI. Cost-effectiveness analysis of a rotavirus immunization program for the United States. Pediatrics 1996; 96:609-615.

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Published

24/06/96

How to Cite

Bishop, Ruth, and Graeme Barnes. 1996. “Rotavirus Infection - the Need for a Vaccine”. Communicable Diseases Intelligence 20 (June):296-98. https://doi.org/10.33321/cdi.1996.20.43.

Issue

Vol. 20 (1996)

Section

Editorial

Categories

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