Annual report of the Australian Gonococcal Surveillance Programme, 2002

Authors

  • John Tapsall South Eastern Sydney Area Laboratory Services, Prince of Wales Hospital, High Street, Randwick NSW 2031
  • Australian Gonococcal Surveillance Programme

DOI:

https://doi.org/10.33321/cdi.2003.27.43

Keywords:

surveillance, Neiserria gonorrhoeae, antimicrobial resistance, gonorrhoea, antibiotics, quinolone, penicillin, spectinomycin, cephalosporin

Abstract

The Australian Gonococcal Surveillance Programme (AGSP) monitors the antibiotic susceptibility of Neisseria gonorrhoeae isolated in all states and territories. In 2002 the in vitro susceptibility of 3,861 isolates of gonococci from public and private sector sources was determined by standardised methods. Antibiotic susceptibility patterns again varied considerably between jurisdictions and regions. Resistance to the penicillins nationally was at 18 per cent but ranged up to 22 per cent in larger urban centres. Quinolone resistance in gonococci (QRNG) remained widespread. Nationally 10 per cent of all isolates were QRNG, and most of this resistance was at high MIC levels. All isolates remained sensitive to spectinomycin. A small number of isolates demonstrated some decreased susceptibility to ceftriaxone (MIC 0.06 mg/L or more) and were concentrated in New South Wales. Patterns of infection were unaltered from previous years. A high proportion of gonococci examined in larger urban centres were from male patients and rectal and pharyngeal isolates were common. In other centres and in rural Australia the male to female ratio of cases was lower, and most isolates were from the genital tract. Commun Dis Intell 2003;27:189-195.

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References

Tapsall J. Antibiotic resistance in Neisseria gonorrhoeae. World Health Organization, Geneva. WHO/CDS/CSR/DRS/2001.3. Available from: http://www.who.int/drugresistance/Antimicrobial_resistance_in_Neisseria_gonorrhoeae.pdf.

Australian Gonococcal Surveillance Programme. Penicillin sensitivity of gonococci in Australia: the development of an Australian Gonococcal Surveillance Programme. Br J Vener Dis 1984,60:226-230.

Australian Gonococcal Surveillance Programme. Use of a quality assurance scheme in a long-term multicentric study of antibiotic susceptibility of Neisseria gonorrhoeae. Genitourin Med 1990,66:437-444.

Ropp PA, Hu M, Olesky M, Nicholas RA. Mutations in ponA, the gene encoding penicillin-binding protein1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. Antimicrob Agent Chemother 2002; 46:769-777.

Ng L-K, Sawatzky P, Martin IE, Booth S. Characterization of ciprofloxacin resistance in Neisseria gonorrhoeae in Canada. Sex Transm Dis 2002;29;780-788.

Tapsall JW. Perspectives on gonococcal disease in Australia, 1999. In: Asche V, editor. Recent advances in microbiology 1999. Volume 7. The Australian Society for Microbiology Inc, Melbourne pp171-196.

The World Health Organization Western Pacific Gonococcal Antimicrobial Surveillance Programme. Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific Region, 2000. Commun Dis Intell 2001;25:274-276.

Shultz TR, Tapsall JW, White PA. Correlation of in vitro susceptibilities to newer quinolones of naturally occurring quinolone-resistant Neisseria gonorrhoeae strains with changes in GyrA and ParC. Antimicrob Agent Chemother 2001;45:734-738.

Akasaka S, Muratani T, Kobayashi T, Yamada Y, Inatomi H, Takahashi K, et al. Gonococcal urethritis and cervicitis caused by CZRNG (cefozopran-resistant Neisseria gonorrhoeae)-clinical failure of cases treated with expanded spectrum cephems, fluoroquinolones and minocycline. Abstracts 13th International Pathogenic Neisseria meeting, Oslo, 2002: p327. Available from: http://neisseria.org/ipnc/2002.shtml

Muratani T, Kobayashi T, Yamada Y, Akasaka S, Inatomi H, Takahashi K, Matsumoto T. Prevalence of super multi-drug resistant Neisseria gonorrhoeae CZRNG (cefozopran-resistant N. gonorrhoeae) in Japan Abstracts 13th International Pathogenic Neisseria meeting, Oslo, 2002, p375. Available from: http://neisseria.org/ipnc/2002.shtml

Ameyama S, Onodera S, Takahata M, Minami S, Maki N, Endo K, et al. Mosaic-like structure of penicillin-binding protein 2 gene (penA) in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime. Antimicrob Agent Chemother 2002;46:3744-3749.

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Published

30/06/03

How to Cite

Tapsall, John, and Australian Gonococcal Surveillance Programme. 2003. “Annual Report of the Australian Gonococcal Surveillance Programme, 2002”. Communicable Diseases Intelligence 27 (June):189-95. https://doi.org/10.33321/cdi.2003.27.43.

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