Annual report of the Australian Gonococcal Surveillance Programme, 2004

Authors

  • Australian Gonococcal Surveillance Programme
  • John Tapsall Department of Microbiology, South Eastern Sydney Area Laboratory Services, The Prince of Wales Hospital, High Street, Randwick, NSW 2031

DOI:

https://doi.org/10.33321/cdi.2005.29.12

Keywords:

antibiotic resistance, disease surveillance, Neisseria gonorrhoeae

Abstract

The Australian Gonococcal Surveillance Programme monitors the antibiotic susceptibility of Neisseria gonorrhoeae isolated in all states and territories. In 2004, the in vitro susceptibility of 3,640 isolates of gonococci from public and private sector sources was determined by standardised methods. Different antibiotic susceptibility patterns were again seen in the various jurisdictions and regions. Resistance to the penicillins nationally was 22 per cent and, with the exception of the Northern Territory, ranged between 12 and 30 per cent. Resistance to quinolones was found in all jurisdictions in a larger proportion of strains and with higher MICs. Nationally, 23 per cent of all isolates were ciprofloxacin-resistant, and most of this resistance was at high MIC levels. All isolates remained sensitive to spectinomycin. A small number of isolates showed some decreased susceptibility to ceftriaxone (MIC 0.06 mg/L or more) and were again concentrated in New South Wales. A high proportion of gonococci examined in larger urban centres were from male patients and rectal and pharyngeal isolates were common. In other centres and in rural Australia the male to female ratio of cases was lower, and most isolates were from the genital tract. Commun Dis Intell 2005;29:136–141.

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References

Tapsall J. Antibiotic resistance in Neisseria gonorrhoeae. World Health Organization, Geneva. WHO/CDS/CSR/DRS/2001.3. Available from: http://www.who.int/csr/drugresist/Antimicrobial_resistance_in_Neisseria_gonorrhoeae.pdf

Akasaka S, Muratani T, Inatomi H, Takahasahi K, Matsumoto T. Emergence of cephem- and aztreonam-high-resistant Neisseria gonorrhoeae that does not produce beta-lactamase. J Infect Chemother 2001;7:49–50.

Muratani T, Akasaka S, Kobayashi T, Yamada Y, Inatomi H, Takahashi K, et al. Outbreak of cefozopran (penicillin, oral cephems, and aztreonam)-resistant Neisseria gonorrhoeae in Japan. Antimicrob Agents Chemother 2001;45:3603–3606.

Wang SA, Lee MV, O'Connor N, Iverson CJ, Ohye RG, Whiticar PM, et al.. Multidrug-resistant Neisseria gonorrhoeae with decreased susceptibility to cefixime – Hawaii, 2001. Clin Infect Dis 2003;37:849–852.

Ito M, Deguchi T, Mizutani KS, Yasuda M, Yokoi S, Ito S, et al.. Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in Central Japan. Antimicrob Agents Chemother 2005;49:137–143.

Australian Gonococcal Surveillance Programme. Penicillin sensitivity of gonococci in Australia: the development of an Australian gonococcal surveillance programme. Br J Vener Dis 1984,60:226–230.

Tapsall JW. Use of a quality assurance scheme in a long-term multicentric study of antibiotic susceptibility of Neisseria gonorrhoeae. Genitourin Med 1990,66:8–13.

Ropp PA, Hu M, Olesky M, Nicholas RA. Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. Antimicrob Agents Chemother 2002;46:769–777.

The WHO Western Pacific Gonococcal Antimicrobial Surveillance Programme. Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific Region, 2003. Commun Dis Intell 2005;29:62–64.

Ameyama S, Onodera S, Takahata M, Minami S, Maki N, Endo K, et al. Mosaic-like structure of penicillin-binding protein 2 gene ( penA) in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime. Antimicrob Agents Chemother 2002;46:3744–3749.

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Published

01/06/05

How to Cite

Australian Gonococcal Surveillance Programme, and John Tapsall. 2005. “Annual Report of the Australian Gonococcal Surveillance Programme, 2004”. Communicable Diseases Intelligence 29 (June):136-41. https://doi.org/10.33321/cdi.2005.29.12.

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