Annual report of the Australian Gonococcal Surveillance Programme, 2005
DOI:
https://doi.org/10.33321/cdi.2006.30.16Keywords:
antimicrobial resistance, disease surveillance, gonococcal infection, Neisseria gonorrhoeaeAbstract
The Australian Gonococcal Surveillance Programme monitors the antibiotic susceptibility of Neisseria gonorrhoeae isolated in all States and Territories. In 2005 the in vitro susceptibility of 3,886 isolates of gonococci from public and private sector sources was determined by standardised methods. Different antibiotic susceptibility patterns were again seen in the various jurisdictions and regions. Resistance to the penicillins nationally was 29.5 per cent and, with the exception of the Northern Territory, ranged between 14 and 47 per cent. Quinolone resistance in gonococci increased with resistance to this agent found in all jurisdictions and in a larger proportion of strains and with higher MICs. Nationally, 29 per cent of all isolates were ciprofloxacin-resistant and most of this resistance was at high minimal inhibitory concentration (MIC) levels. All isolates remained sensitive to spectinomycin. Slightly more than one per cent of isolates showed some decreased susceptibility to ceftriaxone (MIC 0.06 mg/L or more). A high proportion of gonococci examined in larger urban centres were from male patients and rectal and pharyngeal isolates were common. In other centres and in rural Australia the male to female ratio of cases was lower, and most isolates were from the genital tract. Commun Dis Intell 2006;30:205–210.
Downloads
References
Australian Gonococcal Surveillance Programme. Penicillin sensitivity of gonococci in Australia: the development of an Australian Gonococcal Surveillance Programme. Br J Vener Dis 1984;60:226–230.
Tapsall JW. Monitoring antimicrobial resistance for public health action. Commun Dis Intell 2003;27:S70–S74.
Australian Gonococcal Surveillance Programme. Annual report of the Australian Gonococcal Surveillance Programme, 2004. Commun Dis Intell 2005;29:136–141.
Tapsall J. Antibiotic resistance in Neisseria gonorrhoeae. World Health Organization, Geneva. 2001. WHO/CDS/CSR/DRS/2001.3. Available from: http://www.who.int/csr/drugresist/Antimicrobial_resistance_in_Neisseria_gonorrhoeae.pdf Accessed 7 May 2006.
Akasaka S, Muratani T, Inatomi H, Takahasahi K, Matsumoto T. Emergence of cephem- and aztreonam-high-resistant Neisseria gonorrhoeae that does not produce beta-lactamase. J Infect Chemother 2001;7:49–50.
Muratani T, Akasaka S, Kobayashi T, Yamada Y, Inatomi H, Takahashi K, et al. Outbreak of cefozopran (penicillin, oral cephems, and aztreonam)-resistant Neisseria gonorrhoeae in Japan. Antimicrob Agent Chemother 2001;45:3603–3606.
Wang SA, Lee MV, O’Connor N, Iverson CJ, Ohye RG, Whiticar PM, et al. Multidrug-resistant Neisseria gonorrhoeae with decreased susceptibility to cefixime—Hawaii, 2001. Clin Infect Dis 2003;37:849–852.
Ito M, Deguchi T, Mizutani K-S, Yasuda M, Yokoi S, Ito S-I, et al. Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in central Japan. Antimicrob Agent Chemother 2005;49:137–143.
The WHO Western Pacific Gonococcal Antimicrobial Surveillance Programme. Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific Region, 2004. Commun Dis Intell 2006;30:129–132.
Tapsall J, and members of the National Neisseria Network of Australia. Antimicrobial testing and applications in the pathogenic Neisseria. In: Merlino J, ed. Antimicrobial susceptibility testing: methods and practices with an Australian perspective. Australian Society for Microbiology, Sydney, 2004. pp 175–188.
Australian Gonococcal Surveillance Programme. Use of a quality assurance scheme in a long-term multicentric study of antibiotic susceptibility of Neisseria gonorrhoeae. Genitourin Med 1990;66:437–444.
Ropp PA, Hu M, Olesky M, Nicholas RA. Mutations in ponA, the gene encoding penicillin-binding protein1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. Antimicrob Agent Chemother 2002;46:769–777.
World Health Organization. Surveillance standards for antimicrobial resistance. World Health Organization, Geneva, 2002. WHO/CDS/CSR/DRS/2001.5. Available from: http://www.who.int/drugresistance/publications/WHO_CDS_CSR_DRS_2001_5/en/index.html Accessed 7 May 2006.
Smith DW, Tapsall JW, Lum G. Guidelines for the use and interpretation of nucleic acid detection tests for Neisseria gonorrhoeae in Australia: a position paper on behalf of the Public Health Laboratory Network. Commun Dis Intell 2005;29:358–365.
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2006 Communicable Diseases Intelligence

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
