Australian Group on Antimicrobial Resistance Hospital-onset Staphylococcus aureus Surveillance Programme annual report, 2011

Authors

  • Geoffrey W Coombs Australian Collaborating Centre for Enterococcus and Staphylococcus Species (ACCESS) Typing and Research, School of Biomedical Sciences, Curtin University, Perth, Western Australia; Department of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, WA, Royal Perth Hospital, Perth, Western Australia
  • Graeme R Nimmo Division of Microbiology, Pathology Queensland Central Laboratory, Herston Hospitals Campus, Herston, Queensland
  • Julie C Pearson Australian Collaborating Centre for Enterococcus and Staphylococcus Species (ACCESS) Typing and Research, School of Biomedical Sciences, Curtin University, Perth, Western Australia; Department of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, WA, Royal Perth Hospital, Perth, Western Australia
  • Peter J Collignon Infectious Diseases Unit and Microbiology Department, The Canberra Hospital, Garran, Australian Capital Territory
  • Jan M Bell Department of Microbiology and Infectious Diseases SA Pathology, Women’s and Children’s Hospital, North Adelaide, South Australia
  • Mary-Louise McLaws Healthcare Associated Infection and Infectious Diseases Control, University of New South Wales, Sydney, New South Wales
  • Keryn J Christiansen Australian Collaborating Centre for Enterococcus and Staphylococcus Species (ACCESS) Typing and Research, School of Biomedical Sciences, Curtin University, Perth, Western Australia; Department of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, WA, Royal Perth Hospital, Perth, Western Australia
  • John D Turnidge Department of Microbiology and Infectious Diseases SA Pathology, Women’s and Children’s Hospital, North Adelaide, South Australia
  • Australian Group on Antimicrobial Resistance

DOI:

https://doi.org/10.33321/cdi.2013.37.32

Keywords:

antimicrobial resistance surveillance, Staphylococcus aureus, hospital-onset infections, methicillin susceptible, methicillin resistant

Abstract

In 2011, the Australian Group on Antimicrobial Resistance (AGAR) conducted a period-prevalence survey of clinical Staphylococcus aureus isolated from hospital inpatients. Twenty-nine microbiology laboratories from all states and mainland territories participated. Specimens were collected more than 48 hours post-admission. Isolates were tested by Vitek2® antimicrobial susceptibility card (AST-P612 card). Nationally, the proportion of S. aureus that were methicillin-resistant S. aureus (MRSA) was 30.3%; ranging from 19.9% in Western Australia to 36.8% in New South Wales/Australian Capital Territory. Resistance to the non-ß-lactam antimicrobials was common except for rifampicin, fusidic acid, high-level mupirocin and daptomycin. No resistance was detected for vancomycin, teicoplanin or linezolid. Antibiotic resistance in methicillin susceptible S. aureus (MSSA) was rare apart from erythromycin (13.2%) and there was no resistance to vancomycin, teicoplanin or linezolid. Inducible clindamycin resistance was the norm for erythromycin resistant, clindamycin intermediate/susceptible S. aureus in Australia with 90.6% of MRSA and 83.1% of MSSA with this phenotype having a positive double disc diffusion test (D-test). The proportion of S. aureus characterised as being healthcare-associated MRSA (HA-MRSA) was 18.2%, ranging from 4.5% in Western Australia to 28.0% in New South Wales/Australian Capital Territory. Four HA-MRSA clones were characterised and 98.8% of HA-MRSA isolates were classified as either ST22-IV [2B] (EMRSA-15) or ST239-III [3A] (Aus-2/3 EMRSA). Multiclonal community-associated MRSA (CA-MRSA) accounted for 11.7% of all S. aureus. In Australia, regional variation in resistance is due to the differential distribution of MRSA clones between regions, particularly for the major HA-MRSA clone, ST239-III [3A] (Aus-2/3 EMRSA), which is resistant to multiple non-ß-lactam antimicrobials. Commun Dis Intell 2013;37(3):E210–E218.

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Published

01/09/13

How to Cite

Coombs, Geoffrey W, Graeme R Nimmo, Julie C Pearson, Peter J Collignon, Jan M Bell, Mary-Louise McLaws, Keryn J Christiansen, John D Turnidge, and Australian Group on Antimicrobial Resistance. 2013. “Australian Group on Antimicrobial Resistance Hospital-Onset Staphylococcus Aureus Surveillance Programme Annual Report, 2011”. Communicable Diseases Intelligence 37 (September):210-18. https://doi.org/10.33321/cdi.2013.37.32.

Issue

Vol. 37 (2013)

Section

Annual report

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